ACE inhibitors

All ACE inhibitors except captopril and lisinopril are prodrugs


Enalapril has a half life on 1.3 hours only but enalaprilat has a halflife of 11 hours

Lisinopril is lysine analogue of enalapril with half life of 12 hours.

All ACE inhibitors are cleared as intact compound by kidney except fosinopril and moexipril.

Leave a Reply

%d bloggers like this: