Syphilis/Primary Chancre Treponema pallidum Incubation period of 9-90 days Usually single lesion Papule, which maybe superficial or deep Edges are sharply demarcated elevated, round or oval. Induration is firm Pain is uncommon Firm nontender bilateral lymphadenopathy Chancroid Hemophilus ducreyi Incubation …

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Type I lepra reaction/Reverse lepra reaction Tuberculoid type Type IV hypersensitivity reaction DOC is corticosteroids Type II lepra reaction/ENL Erethema Nodosum Leprosum Lepromatous leprosy Type III hypersensitivity reaction DOC is cortico steroids Thalidomide and clofazimine is used in recurrent/persistent attacks.

Acanthosis Nigricans-Gastrointestinal Adenocarcinoma. Necrolytic migratory erythema-Gastrinoma. Dermatomyositis-Bronchogenic carcinoma,Carcinoma Breast,Ca Genitourinary tract. Pemphigus-Thymoma,lymphoma. Migratory thrombophlebitis-Ca Lung,Ca Pancreas