Causes of Micovesicular and macrovesicular fatty liver

Microvesicular hepatic steatosis

  • Reyes syndrome
  • Acute fatty liver of pregnancy
  • Jamaican vomiting sickness
  • Phosphorous,petrochemicals
  • Drugs
  1. Sodium valproate
  2. Tetracycline
  3. Nucleoside analogues

Macrovesicular hepatic steatosis

  • Alcohol
  • Insulin resistance
  • Non alcoholic steato hepatitis(NASH)
  • Total parenteral nutrition
  • Intestinal bypass surgeries
  • Inflammatory bowel disease
  • Starvation
  • Drugs
  1. Aspirin
  2. Methotrexate
  3. Vitamin A
  4. Steroids
  5. Amiodarone
  6. Calcium channel blockers

 

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