Corticosteroids

  • Zona Glomerulosa-Mineralocorticoids
  • Zona Fasciculata-Glucocorticoids
  • Zona Reticularis-Sex corticoids
  • GFR from outside to inside.

Points to remember

  1. Maximum glucocorticoid activity- Dexamethasone
  2. Maximum mineralocorticoid activity- Aldosterone
  3. Glucocorticoid with maximum mineralocorticoid action-Hydrocortisone
  4. Least potent Glucocorticoid- Cortisone
  5. Most potent Glucocorticoid- Betamethasone
  6. Selective mineralocorticoid action(zero glucocorticoid action)- DOCA
  7. Selective glucocorticoid action(Zero mineralocorticoid action)- Methyl prednisolone,triamcinolone,paramethasone,dexamethasone,betamethasone
  8. Steroid with maximum topical activity- Triamcinolone acetonide

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