Enzyme Inducers and Inhibitors

what are Enzyme Inducers?

Enzyme Inducers are drugs which increase the metabolism of other drugs in the body.

Mnemonics for Eznzyme inducers :

GPRS Cell Phone

G-Griseofulvin

P-Phenytoin

R-Rifampicin

S-Smoking

Cell-Carbamazepine

Phone-Phenobarbitone

As you can see most of the antiepileptic drugs cause enzyme Induction, just like inducing an episode of epilepsy!

Another mnemonic for enzyme inducers is

SCRAP GP

Sulphonylureas
Carbamezapine
Rifampin
Alcohol
Phenytoin
Griseofulvin
Phenobarbital

What are the Enzyme Inhibitors?

Enzyme inhibitors are drugs which decrease the metabolism of drugs by inhibiting microsomal enzymes.

Mnemonics for enzyme inhibitors :

Vitamin K Cannot Cause Enzyme Inhibition

Vit-Valproate

K-Ketoconazole

Cannot-Cimetidine

Cause-Ciprofloxacin

Enzyme-Erythromycin

Inhibition-INH

Another mnemonic for enzyme Inhibitors is:

SICKFACES.COM

Sodium valproate
Isoniazid
Cimetidine
Ketoconazole
Fluconazole
Alcohol
Chloramphenicol
Erythromycin
Sulfonamides
Ciprofloxacin
Omeprazole
Metronidazole

 

  1. imoni onuh james

    This is awsome!,I just got this mnemonic best!.Thanks and keep the good work steady!

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