General anaesthetics

This is the most confusing topic in Pharmacology,because of the similarity in names of drugs and mechanisms of actions this topic can be considered even more difficult to master than Skeletal Muscle relaxants.

Inhalational agents

N2O maximum MAC and minimum potency.

Methoxyflurane is the most potent.

Desflurane is fastest acting(Minimum blood gas partition coefficient)

Methoxyflurane is slowest acting.

Maximum respiratory depression with enflurane

Maximum bronchodilation with halothane in asthmatics and sevoflurane in non asthmatics.

Isoflurane is agent of choice for producing controlled hypotension

Cyclopropane increases BP so used in shock.

Isoflurane is DOC in cardiac patients.

Halothane CI in pheochromocytoma.

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