GIT hormones,their actions and sites of action.
Posted by admin
on August 29, 2011
Cholecystokinin(CCK)
- Secreted from I cells
- Acts on GB and pancreas
- Increase enzyme secretion
- Increase contraction
Gastro Intestinal Peptide(GIP)
- Secreted from K cells
- Acts on Pancreas
- Increase insulin
- Decrease fluid absorption
Gherlin
- Secreted from stomach
- Increase food intake
- Increase GH secretion
Gastrin
- Secreted from G cells
- Acts on parietal cells
- Increase H+ secretion
Gastrin Releasing Peptide(GRP)
- Secreted from vagal nerve end
- Acts on G cells
- Increase gastrin secretion
Guanylin
- Secreted from ileum and colon
- Acts on small and large intestines
- Increased fluid absorption
Motilin
- Secreted from Mo cells
- Acts on upper GI
- Smooth muscle contraction
Neurotensin
- Present all over intestine
- Acts on intestinal smooth muscles
- Increase histamine release
Peptide YY
- Secreted from ileum and colon
- Acts on stomach and pancreas
- Decrease acid secretion and increase enzyme fluid
Secretin
- From S cells
- Acts on pancreas and stomach
- Increase bicarbonate and fluid
- Decrease acid secretion from stomach
Somatostatin
- Secreted from D cells
- Acts on stomach,pancreas,intestne,liver
- Decrease secretion and increase fluid
Substance -P
- From enteric neurons
- Acts on enteric neurons
VIP
- From ENS neurons
- Acts on SI and pancreas
- Increase secretion
- Decrease smooth muscle relaxation.
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