HLA types associated with various diseases is a hot favorite question of many PG exams. So pooling all these HLA types and the diseases associated with them seemed to be a good idea. Given below is a list of most frequently asked HLA types.
Diseases and associated HLA
- Multiple sclerosis- HLA DR2
Narcolepsy- HLA DR2
Goodpasture’s syndrome- HLA DR2
Sjogrens- HLA DR3
Dermatitis herpetiformis- HLA DR3
Celiac disease- HLA DR3
Rheumatoid arthritis- HLA DR4
Behcets disease – HLA B5
Congenital adrenal hyperplasia- HLA B47
SLE- HLA DR2,DR3
Type 1 Diabetes – HLA DR2,DR3,DR4
Hyperthyroidism – HLA B8,DR3
Myasthenia gravis- HLA B8,DR3
Tuberculoid leprosy- HLA B8,DR3
VKH syndrome- HLA DW 15,DR4
Conditions associated with HLA B27
- Ankylosing spondylitis
- Psoriatic arthritis
- Reiters syndrome
- Reactive arthritis(Yersinia, salmonella,gonococci)
- JRA(pauci articular)
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