Autosomal dominant GI polyposis syndromes
High malignant potential
These are histologically adenomas
Familial polyposis Coli
Large Intestine
Gardner’s syndrome
Large intestine>SI.
Also associated with
- Osteomas
- Lipomas
- Fibromas
- Epidermal cyst
- Ampullary ca
- Desmoid
Turcot’s sydrome
LI, associated with brain tumours.
Low malignant potential
Mainly hamartamatous polyps on histology
Peutz Jeghers polyposis
SI>LI>stomach
Also associated with
Mucocutaneous pigmentations
Tumours of ovary,breast pancreas,endometrium.
Juvenile polyposis syndrome
LI>SI>Stomach
Associated with congenital anomalies
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