Prerequisite for drugs to be eliminated by dialysis

Drugs eliminated by dialysis have the following features

  1. Low molecular mass<500da
  2. High water solubility
  3. Low plasma protein binding
  4. Small volume of distribution
  5. Long half life
  6. High dialysis clearance relative to total body clearance

Drugs which can be cleared by dialysis

  1. Acetone,Atenolol
  2. Barbiturates,Bromide
  3. Chloral hydrate
  4. Ethanol,Ethylene glycol,Isopropyl alcohol,Methanol
  5. Lithium
  6. Procainamide,Theophylline
  7. Salicylates,Sotalol,Heavy metals

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