Master Of Medicine

Papillary carcinoma

• Affects columnar cells of thyroid gland
• Most common type 80%
• Common in younger age group
• Slow growing nodule,metastasis to cervical LN
• Orphan annie(groundglass)nuclei.
• Psammoma bodies.
• Increased incidence in radiation exposure
• Excellent prognosis

Follicular carcinoma

• Affects cuboid cells in follicles
• 10% of thyroid cancers
• MC in older patients
• Mets to liver,lung,bone,brain.

Medullary carcinoma

• Affects parafollicular C cells
• Produces calcitonin
• Associated with MEN2a and MEN2
• Prognosis worse in old patients,mets common at diagnosis.

Anaplastic carcinoma

• Poorly differentiated neoplasm
• Very aggressive,local invasion causes hoarseness,dysphagia.
• Very poor prognosis