Thyroid carcinoma
Posted by admin
on September 27, 2010
Papillary carcinoma
- Affects columnar cells of thyroid gland
- Most common type 80%
- Common in younger age group
- Slow growing nodule,metastasis to cervical LN
- Orphan annie(groundglass)nuclei.
- Psammoma bodies.
- Increased incidence in radiation exposure
- Excellent prognosis
Follicular carcinoma
- Affects cuboid cells in follicles
- 10% of thyroid cancers
- MC in older patients
- Mets to liver,lung,bone,brain.
Medullary carcinoma
- Affects parafollicular C cells
- Produces calcitonin
- Associated with MEN2a and MEN2
- Prognosis worse in old patients,mets common at diagnosis.
Anaplastic carcinoma
- Poorly differentiated neoplasm
- Very aggressive,local invasion causes hoarseness,dysphagia.
- Very poor prognosis
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