Translocations and associated tumours

Sarcomas

t(11:22)

Ewings sarcoma family

Classical Ewings sarcoma

PNET

Askins tumour

t(12:22)

Clear cell sarcoma

Malignant melanoma of soft tissues

t(12:16)

Myxoid liposarcoma

t(2:13)

Alveolar rhabdomyosarcoma

t(x:18)

Synovial cell sarcoma

Lymphomas

t(11:14)-Mantle cell lymphoma

t(14:18)- Follicular lymphoma

t(8:14)- Burkitts lymphoma(B cell ALL)

t(11:18)-MALT lymphoma

t(14:15)-CLL/ Small lymphocytic lymphoma

t(9:22)

Precursor B cell ALL(Pre B ALL)

Chronic Myeloid Leukemia(CML)

t(15:17)- Acute Promyelocytic leukemia(ALL M3)

t(8:21)-Acute Myeloblastic Leukemia with maturation(AML-M2)

ALL

Pre B ALL-L1,L2-75%cases t(9:22),t(4:11),t(1:9)

T Cell ALL- 20%-L1,L2-14q11,7q34

B cell ALL-5%-L3 t(8:14),t(2:22),t(2:8)

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